Pyridinium-based tripodal chemosensor in visual sensing of AMP in water by indicator displacement assay (IDA).

نویسندگان

  • Kumaresh Ghosh
  • Sk Sarfaraj Ali
  • Avik Ranjan Sarkar
  • Asmita Samadder
  • Anisur Rahman Khuda-Bukhsh
  • Ioannis D Petsalakis
  • Giannoula Theodorakopoulos
چکیده

A simple pyridinium-based tripodal chemosensor, 1, effectively recognizes AMP over ATP and ADP through indicator displacement assay (IDA) technique in water at pH 6.4. The good recognition of 1 is due to the better accommodation of AMP at the core of 1 as well as functional interaction involving hydrogen bonding and charge-charge interaction. The sensor 1 also recognizes intracellular AMP.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Pyridinium-based symmetrical diamides as chemosensors in visual sensing of citrate through indicator displacement assay (IDA) and gel formation.

The design and synthesis of pyridinium-based symmetrical diamides 1 and 2 along with their anion binding studies through 'indicator-diplacement assay' are reported. Both the chemosensors effectively respond in in CH(3)CN-H(2)O (4 : 1 v/v) at pH = 6.3 for the selective naked-eye detection of citrate. Additionally, chemosensor 2 (c = 6.29 × 10(-3) M) forms a stable gel only with citrate in CH(3)C...

متن کامل

Discriminate sensing of pyrophosphate using a new tripodal tetramine-based dinuclear Zn(II) complex under an indicator displacement assay approach.

In this research, the dinuclear Zn(ii) complex of anthracene based tripodal tetramine Zn2L was synthesized, and its sensing abilities towards anions was investigated using the indicator displacement assay (IDA) approach with four complexometric indicators: pyrocatechol violet (PV), bromopyrogallol red (BPG), methylthymol blue (MTB) and xylenol orange (XO). UV-vis spectrophotometry results indic...

متن کامل

Carbohydrate sensing with a metal-based indicator displacement assay.

A Pd-based indicator displacement assay for the fluorimetric sensing of carbohydrates has been developed. The assay allows the detection of saccharides in the low millimolar concentration range in water at neutral pH.

متن کامل

Reaction-based Indicator displacement Assay (RIA) for the selective colorimetric and fluorometric detection of peroxynitrite.

Using the self-assembly of aromatic boronic acids with Alizarin Red S (ARS), we developed a new chemosensor for the selective detection of peroxynitrite. Phenylboronic acid (PBA), benzoboroxole (BBA) and 2-(N,N-dimethylaminomethyl)phenylboronic acid (NBA) were employed to bind with ARS to form the complex probes. In particular, the ARS-NBA system with a high binding affinity can preferably reac...

متن کامل

Oral & Poster Presentation Abstracts

Katheryn Adam, Chemistry Faculty Mentor: Marco Bonizzoni, Chemistry An off-the-shelf sensing system for physiologically relevant phosphates We have developed a chemical sensing system that can differentiate biologically relevant phosphates (nucleoside diphosphates, pyrophosphate) in neutral water solution using only commercially available components. Our approach uses a common fluorescent indic...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 11 34  شماره 

صفحات  -

تاریخ انتشار 2013